Lecture by Dr. Qian Wu from Astbury Centre for Structural Molecular Biology, University of Leeds, UK entitled „BRCT domain in DNA damage response“ from the CAPSID Seminar Speaker Series, will take place on 20 May 2021 at 2 p.m. via online broadcasting via the ZOOM application.
AREAS OF EXPERTISE:
DNA damage response; DNA repair; Structural biology; DNA damage
SEMINAR ANNOTATION:
DNA damage occurs due to exogenous and endogenous triggers, including ionizing radiations and by-product of normal cellular functions. Cells rely on the DNA damage response (DDR), a highly regulated cellular signalling network, to deal with these damages. Unrepaired damages can lead to genome instability and cell death. BRCT (named as BRCA1-C-Terminal) domain is a common domain found in many key DDR proteins such as BRCA1, BARD1, 5BP1 and DNA ligase IV. This talk will discuss my studies about the structure, motif-recognition and function of BRCT domain in DNA damage response network.
More information about lecture and registration on the project web site: https://capsid.vbcf.ac.at/events/
ANNOTATION and SUBMISSION DATA OF THE LECTURE (pdf)
Funding programme of the CAPSID project: Interreg V-A Slovakia-Austria
Organizers:
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